Family: Roshen was an illegitimate child and as such he never knew his real father. His mother passed him off as her husband's son though later she poisoned him, for all Roshen knows, she could have poisoned his real father too. His mother is still alive however he has very little contact with her because they do not really get along. She is very critical of her son and she checks up on him occasionally to make sure he's "doing his job right".
Friends: Roshen has absolutely none of these. The closest he comes to friends are allies and they resent him for his cold and arrogant personality. In short the few allies he does have are those allies of strictly business.
Enemies: Just as Roshen has no friends, he has plenty enemies. There are people all over the Ages who probably want him dead or worse. He is aware of many of these enemies and handles them with threats and blackmail or disease however there may be some hiding out somewhere that he doesn't know about. These enemies may even be right under his nose.
Lovers: Roshen has had no lovers and, honestly, he doesn't care to. Science is his first love and it would be very hard to get him to even consider someone romantically. That person would have to be at least as intelligent as he was and what's more is he would have to recognize that they were. However, even if he did find someone his science would always come first when it came down to it.